Full list of Publications:

Selected Publications

1. Chin ML, Zhang H, Au CK, Luk WL, Cai Z, Chan W*, Aristolochic Acids and Aristoloxazines are Widespread in the Soil of Aristolochiaceae Herb Cultivation Fields, Environ Sci Technol, Accepted.
   
2. Ham YH, Cheng J, Nagl S, Yu JZ, Cai Z, Chan W*, (2024) Surgical Face Mask as an Air Sampling Device for Assessing Personal Exposure to Airborne Antimicrobial Resistance Gene-Bearing Bacteria, Anal Chem, 96(42):17021-17026.
   
3. Pan G, Au CK, Ham YH, Yu JZ, Cai Z, Chan W*, (2024) Urinary Thioproline and Thioprolinyl Glycine as Specific Biomarkers of Formaldehyde Exposure in Humans. Environ Sci Technol, 2024 Sep 2.  doi: 10.1021/acs.est.4c06921. Online ahead of print.
   
4. Ham YH, Chin ML, Pan G, Wang S, Pavlović NM, Chan W*, (2024) Positive Feedback Mechanism in Aristolochic Acid I Exposure-Induced Anemia and DNA Adduct Formation: Implications for Balkan Endemic Nephropathy. J Agric Food Chem, 72(32):18155-18161.
   
5. Guo W, Kwok HC, Griffith S, Nagl S, Milovanović D, Pavlović M, Pavlović NM, Yu JZ, Dedon PC, Chan W*, (2024) Combustion-Derived Pollutants Linked with Kidney Disease in Low-Lying Flood-Affected Areas in the Balkans. Environ Sci Technol, 58(26):11301-11308 .
   
6. Chin ML, Au CK, Chan CK, Jin L, Živković Stošić Milena, Đorđević Zlatković Miljana, Zlatkovic Dragan, Pavlovic NM, Chan W*, (2023) Fabrication of a Simple and Efficient HPLC Reduction Column for Online Conversion of Aristolochic Acids to Aristolactams Prior to Sensitive Fluorescence Detection. Anal Chem, 95(33): 12365-12372.
   
7. Sun Z, Guo W, Chan CK, Jin L, Griffith S, Yu JZ, Chan W*, (2022) Polyurethane Foam Face Masks as a Dosimeter for Quantifying Personal Exposure to Airborne Volatile and Semi-Volatile Organic Compounds. Chem Res Toxicol, 35(9): 1604-1613.

8. Chan W*, Jin L, (2022) DNA-Protein Cross-Links Formed by Reacting Lysine with Apurinic/Apyrimidinic Sites in DNA and Human Cells: Quantitative Analysis by Liquid Chromatography-Tandem Mass Spectrometry Coupled with Stable Isotope Dilution. Anal Chem, 94(2): 803-810.
9. Jin L, Griffith S, Sun Z, Yu JZ, Chan W*, (2021) On the Flip Side of Mask Wearing: Increased Exposure to Volatile Organic Compounds and a Risk-Reducing Solution. Environ Sci Technol, 55(20): 14095-14104.

10. Chan W*, Guo W, Yu JZ, (2021) Polyurethane-Based Face Mask as a Sampling Device for Environmental Tobacco Smoke. Anal Chem, 93(41): 13912-13918.
    

11. Guo W, Zhang J, Sun Z, Orem W.H, Tatu CA, Radulović NS, Milovanović D, Pavlović NM*, and Chan W*, (2021) Analysis of Polycyclic Aromatic Hydrocarbons and Phthalate Esters in Soil and Food Grains from the Balkan Peninsula: Implication on DNA Adduct Formation by Aristolochic Acid I and Balkan Endemic Nephropathy. Environ Sci Technol, 55(13): 9024-9032.

12. Chan W*, Jin L, Sun Z, Griffith S,* Yu JZ*, (2021) Fabric Masks as a Personal Dosimeter for Quantifying Exposure to Airborne Polycyclic Aromatic Hydrocarbons. Environ Sci Technol, 55(8): 5128-5135.

13. Tung KK, Chan CK, Zhao Y, Chan KKJ, Liu G, Pavlovic NM*, Chan W*, (2020) Occurrence and Environmental Stability of Aristolochic Acids in Groundwater Collected from Serbia: Links to Human Exposure and Balkan Endemic Nephropathy. Environ Sci Technol. 54(3):1554-1561.  (Featured by ACS press release)



14. Chan W*, Ham Y-H, Jin L, Chan H-W, Wong Y-L, Chan C-K, Chung P-Y, (2019) Quantification of a novel DNA-protein crosslink product formed by reacting apurinic/apyrimidinic sites in DNA with cysteine residues in protein by liquid chromatography-tandem mass spectrometry coupled with the stable isotope-dilution method. Anal Chem, 91: 4987-4994.
15. Li W, Chan C-K, Liu Y, Yao J, Branka Mitić, Emina N. Kostic, Biljana S. Milosavljevic, Ivana Davinić, William H Orem, Calin A. Tatu, Peter C. Dedon, Nikola M. Pavlović, and Chan W*, (2018) Aristolochic Acids as Persistent Soil Pollutants: Determination of Risk for Human Exposure and Nephropathy from Plant Uptake. J Agric Food Chem., 66: 11468-11476.



16. Chan W*, Pavlović NM*, Li W, Chan C-K, Liu J, Deng K, Wang Y, Milosavljević B, and Kostić EN, (2016) Quantitation of Aristolochic Acids in Corn, Wheat Grain, and Soil Samples Collected in Serbia: Identifying a Novel Exposure Pathway in the Etiology of Balkan Endemic Nephropathy.J Agric Food Chem., 64: 5928−5934. **Research Article of the Year Award**



17. Li Y, Liu J, Wang Y, Chan H-W, Wang L*, and Chan W*, (2015) Mass spectrometric and spectrophotometric analyses reveal an alternative structure and a new formation mechanism for melanin, Anal. Chem., 7: 7958−7963.
18. Ye Y, Liu H, Horvatovich P, and Chan W*, (2013) Liquid chromatography-electrospray ionization tandem mass spectrometric analysis of 2-alkylcyclobutanones in irradiated chicken by pre-column derivatization with hydroxylamine, J. Agric. Food Chem, 61: 5758-5763.
19. Chan W, Chen BZ, Wang LR, Taghizadeh K, Demott MS, Razskazovskiy Y, and Dedon PC*, (2010) Quantification of the 2-deoxyribonolactone and nucleoside 5’-aldehyde products of 2-deoxyribose oxidation in DNA and cells by isotope-dilution gas chromatography mass spectrometry: Differential effects of γ-radiation and Fe2+-EDTA, J. Am. Chem. Soc. 132: 6145-6153.
20. Chan W, Lee KC, Liu N, and Cai ZW, (2007) A sensitive enhanced high performance liquid chromatography fluorescence method for the detection of nephrotoxic and carcinogenic aristolochic acid in herbal medicines, J. Chromatog. A 1164:113-119.

Other Publications

Proteomics

• Chan W*, et al. Proteomics Study of DNA-Protein Crosslinks in Methylmethanesulfonate and Fe2+-EDTA-Exposed Human Cells. Chem Res Toxicol, 2020.
• Chan W*, et al. Proteomic analysis of thioproline misincorporation in Escherichia coli. J Proteomics, 2020.

 

Metabolomics

• Chan W, et al. Liquid chromatography/mass spectrometry for investigating the biochemical effects induced by aristolochic acid in rats: the plasma metabolome. Rapid Commun Mass Spectrom, 2010.
• Chan W, et al. Liquid chromatography/mass spectrometry for metabonomics investigation of the biochemical effects induced by aristolochic acid in rats: the use of information-dependent acquisition for biomarker identification. Rapid Commun Mass Spectrom, 2008.